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The New England Journal of Medicine
Sublingual B12 tablets are particularly useful as they are absorbed in the mouth which bypasses any absorption issues in the bowel (i.e
If youve had a chronic, severe vitamin deficiency for many years, your symptoms will be more significant than they would be after a few weeks of decreased B12 intake
How to supplement when B12 tests are high Be sure you remove all sources of synthetic cyanocobalamin from your diet (supplements & fortified foods) Consider supplementing with iodine, selenium, and molybdenum which helps activate B2 (a B12 transport helper) Consider supplementing with an active B2 form (Riboflavin-5-Phosphate) - a B12 transport cofactor Consider taking intrinsic factor which helps the gut better absorb B12 Consider pulsing 4.5 mg of lithium orotate (2-3x per week) - helps the B12 transport Only supplement with bioidentical active B12 forms - hydroxocobalamin, methylcobalamin, adenosylcobalamin I know my specific COMT & VDR Taq gene details
( 10 ) This high dose ensures your body has what it needs to restore optimal function quickly
Maintenance dosing schedules are less often than the first doses, usually monthly
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